Origins
When was 5-Amino-1MQ created?
5-Amino-1MQ is a small molecule with a quinolinium core. It is not a peptide, and the naming makes that obvious once you read it.
The short answer
| Date | Published around 2018 |
| Who | Reported by academic groups in the United States |
| Where | United States |
| Origin | Designed, not found — it does not occur naturally in this form. |
Where it came from
The name is a chemical description rather than a code: 5-amino-1-methylquinolinium. A quinolinium ring, a methyl group on the nitrogen, an amino group at position 5. Nothing in that describes a chain of amino acids, because there is not one.
It was reported as an inhibitor of nicotinamide N-methyltransferase, an enzyme the compound was designed to resemble a substrate of. The work appears in the literature from around 2018.
It is included in this catalogue and on this page because it is sold beside peptides and frequently described as one. Purity figures and net peptide content mean different things for a small molecule than for a peptide, which is the practical reason the distinction is kept.
Why it is called that
A systematic chemical name, not an acronym: the ring, the methyl group, and where the amino group sits.
Where it stands now
5-Amino-1MQ has not been approved as a medicine anywhere and is not a peptide.
What this page does not say
Nothing above is a statement about what 5-Amino-1MQ does in a body, and none of it is guidance on use. A compound’s history is a record of laboratories and dates; it is not evidence for anything, and the fact that a programme was looking for something is not a finding that it was found.
More on 5-Amino-1MQ
What is 5-Amino-1MQ? · The full timeline · 5-Amino-1MQ — sizes and prices
