Reference
What is MOTS-c?
MOTS-c belongs to a small and unusual class: peptides encoded in mitochondrial DNA rather than in the cell nucleus. Almost every protein in the body is transcribed from nuclear DNA, which makes mitochondrial-derived peptides a genuine curiosity of molecular biology.
Classification
| Type | Peptide |
| Chain length | 16 amino acid residues |
| Family | Mitochondrial-derived peptide |
| Origin | Described in 2015 by researchers at the University of Southern California |
| Supplied as | Lyophilised powder in a sealed vial |
It is sixteen residues long and was only described in 2015, making it one of the more recently characterised compounds in this range. The class it belongs to — mitochondrial-derived peptides — was itself only recognised in the 2000s.
Where it sits by length
At 16 residues, MOTS-c is a mid-length chain, comfortably within peptide territory. The boundary is a convention, not a rule of chemistry — chains up to roughly fifty residues are generally called peptides.
What this page does not cover
Nothing here describes what MOTS-c does, what it is used for, or whether it is safe. We publish analytical results and ship parcels; we give no guidance on dosing, preparation or use, and that applies to our reference pages as much as to the product pages. The person to ask about any of that is a registered prescriber.
Where it came from
MOTS-c was found somewhere nobody had thought to look for a peptide: inside a mitochondrial gene.
2015 — University of Southern California. When was MOTS-c discovered?
More on MOTS-c
- MOTS-c — prices and sizes
- Buying MOTS-c in New Zealand
- When was MOTS-c discovered?
- The MOTS-c certificate of analysis
See MOTS-c in the range · What is a peptide? · Discovery timeline · All reference
